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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AAK1
All Species:
17.58
Human Site:
T27
Identified Species:
55.24
UniProt:
Q2M2I8
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q2M2I8
NP_055726.3
863
93578
T27
S
S
G
G
G
G
S
T
S
G
L
G
S
G
Y
Chimpanzee
Pan troglodytes
XP_001138187
865
93810
T27
S
S
G
G
G
G
S
T
S
G
L
G
S
G
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531855
473
51892
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHJ0
959
103328
S27
S
S
G
G
G
G
S
S
S
G
L
G
S
G
Y
Rat
Rattus norvegicus
P0C1X8
962
103742
S27
S
S
G
G
G
G
S
S
S
G
L
G
S
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417663
953
102927
S27
T
S
G
G
G
G
G
S
G
G
P
G
S
G
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625109
598
65629
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40494
810
91014
Y27
H
H
A
K
I
I
K
Y
L
T
S
G
G
F
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
53.7
N.A.
80.7
79.9
N.A.
N.A.
71.4
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
N.A.
Protein Similarity:
100
99.6
N.A.
54.4
N.A.
83.1
82.7
N.A.
N.A.
77.9
N.A.
N.A.
N.A.
N.A.
50
N.A.
N.A.
P-Site Identity:
100
100
N.A.
0
N.A.
93.3
93.3
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
0
N.A.
100
100
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% F
% Gly:
0
0
63
63
63
63
13
0
13
63
0
75
13
63
0
% G
% His:
13
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
13
13
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
13
0
50
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
63
0
0
0
0
50
38
50
0
13
0
63
0
0
% S
% Thr:
13
0
0
0
0
0
0
25
0
13
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
63
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _